organic chemical reactions
Do enzymes only ever catalyse chemical reactions involving covalent bonds?
A colleague and I were wondering about this. Enzymes are biological catalysts that increase the rate of chemical reactions within the body. I’ve always assumed that these reactions are always covalent, but my colleague was wondering if this is absolutely always the case. I’m pretty sure that interactions with hydrogen bonds aren’t chemical reactions, and that ionic bonding doesn’t really happen in organic chemistry.
That’s a good question. I would consider the only bonds necessary for catalysis to be covalent, since they are “high energy” bonds. I don’t think non-covalent bonds need to be broken for biological purposes, since things like salts are disassociated in water.
Maybe the closest thing would be the synthesis of a metalloenzyme which uses ionic stabilization bonds.
Organic Chemistry reactions – 7 clues from Obi Wan
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